Sequence‐Dependent Fluorescence of DNA‐Hosted Silver Nanoclusters

E. G. Gwinn, Patrick O’Neill, Adán Guerrero, Dirk Bouwmeester, Deborah Kuchnir Fygenson

Advanced Materials · 2008 · 438 citations · 22 references

Concepts

Abstract

DNA-bound silver nanoemitters reside in single-stranded regions of the host DNA. Their fluorescence is sensitive to both the DNA base sequence and its secondary structure. Fluorescence from individual emitters hosted by DNA “hairpins”, which are suitable for incorporation into DNA scaffolds, is detectable using standard epifluorescence techniques.

References

22