Publication | Closed Access
A Lewis Acid Palladium(II)-Catalyzed Three-Component Synthesis of α-Substituted Amides
45
Citations
36
References
2013
Year
Arylboronic AcidsAvailable Building BlocksLewis Acid PalladiumEngineeringNatural SciencesDiversity-oriented SynthesisOrganic ChemistryOrganometallic CatalysisCatalysisChemistryα-Substituted AmidesSynthetic Chemistry
A Lewis acid palladium-catalyzed reaction of amides, aryl aldehydes, and arylboronic acids is described. This new method allows for a practical and general synthesis of α-substituted amides from simple, readily available building blocks.
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