Eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ionic liquids or ionic liquid–water without additional catalyst

Abstract

2,3-Dihydroquinazolin-4(1H)-ones have been synthesized in high to excellent yields through direct cyclocondensation of anthranilamides and aldehydes in ionic liquids (ILs) or one-pot three-component cyclocondensation of isatoic anhydrides, ammonium acetate and aldehydes in ionic liquid–water solvent system without the use of any additional catalyst.