Discovery of non-peptide inhibitors of Plasmepsin II by structure-based virtual screening

Artemisinin Resistance in <i>Plasmodium falciparum</i> Malaria

Arjen M. Dondorp, François Nosten, Poravuth Yi et al. · New England Journal of Medicine · 2009 · 3.5K citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Chloroquine Resistance in <i>Plasmodium falciparum</i> Malaria Parasites Conferred by <i>pfcrt</i> Mutations

Amar Bir Singh Sidhu, Dominik Verdier-Pinard, David A. Fidock · Science · 2002 · 715 citations · Full text

Life Sciences, Genetics, Infectious Diseases +16

Four plasmepsins are active in the <i>Plasmodium falciparum</i> food vacuole, including a protease with an active-site histidine

Ritu Banerjee, Jun Liu, Wandy L. Beatty et al. · Proceedings of the National Academy of Sciences · 2002 · 457 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

A M Silva, Angela Lee, Sergei Gulnik et al. · Proceedings of the National Academy of Sciences · 1996 · 278 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II

Tasir S. Haque, A. Geoffrey Skillman, Christina E. Lee et al. · Journal of Medicinal Chemistry · 1999 · 169 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17