Novel ADAMTS‐13 mutations in an adult with delayed onset thrombotic thrombocytopenic purpura

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

Gallia G. Levy, William C. Nichols, Eric C.‐Y. Lian et al. · Nature · 2001 · 1.8K citations · Full text

Medicine, Genetics, Molecular Genetics +10

Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Joel L. Moake, Christine K. Rudy, Joseph H. Troll et al. · New England Journal of Medicine · 1982 · 1.1K citations

Medicine, Hematology, Pathology +17

Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis

M. Furlan, Rodolfo Robles, B Lamie · Blood · 1996 · 893 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions

Jing-fei Dong, Joel L. Moake, Leticia Nolasco et al. · Blood · 2002 · 848 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura

X. Long Zheng, Dominic W. Chung, Thomas K. Τakayama et al. · Journal of Biological Chemistry · 2001 · 838 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14