Pathoanatomic, Pathophysiologic and Clinical Correlations in Endocarditis

Abstract

A TRUE understanding of disease demands thorough knowledge of the specific pathophysiologic and pathoanatomic processes involved, It is interesting, in this regard, that in only a few of the numerous disorders that affect human beings are the responsible mechanisms sufficiently defined to permit prediction of the clinical pictures. For example, the clinical syndromes and pathological changes associated with atherosclerosis are well known, but the mechanisms involved in their pathogenesis are still matters for debate. Similarly, it is still not clear what occurs in the patient overwhelmed by the staphylococcus, nor are the anatomic and physiologic bases for the symptoms produced . . .