Diagnostic utility of HFE variants in Spanish patients: Association with HLA alleles and role in susceptibility to acute lymphoblastic leukemia

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

John N. Feder, Andreas Gnirke, Zenta Tsuchihashi et al. · Nature Genetics · 1996 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

SNPStats: a web tool for the analysis of association studies

Xavier Solé, Elisabet Guinó, Joan Valls et al. · Bioinformatics · 2006 · 2K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

John N. Feder, David M. Penny, Alivelu Irrinki et al. · Proceedings of the National Academy of Sciences · 1998 · 838 citations

Life Sciences, Genetics, Molecular Biology +15

The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

John N. Feder, Zenta Tsuchihashi, Alivelu Irrinki et al. · Journal of Biological Chemistry · 1997 · 479 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

A population-based study of the biochemical and clinical expression of the H63D hemochromatosis mutation

Peter Gochee, Lawrie W. Powell, Digby J Cullen et al. · Gastroenterology · 2002 · 257 citations · Full text

Medicine, Genetics, Molecular Genetics +8