Intraocular Concentrations of Gatifloxacin and Moxifloxacin in the Anterior Chamber via Diffusion Through the Cornea Using Collagen Shields

Abstract

Gatifloxacin and moxifloxacin showed good penetration into the anterior chamber with no obvious adverse reaction to the cornea. The concentrations in the anterior chamber exceeded the minimal inhibitory concentration (MIC) 90 of most organisms responsible for postoperative endophthalmitis (POE).