Concepedia

Discovery of mitochondria-targeting berberine derivatives as the inhibitors of proliferation, invasion and migration against rat C6 and human U87 glioma cells

Shengnan Fu, Yanqi Xie, Jue Tuo, Yalong Wang, Wenbo Zhu, Sihan Wu, Guangmei Yan, Haiyan Hu

MedChemComm · 2014 · 35 citations · 23 references

DOI

Concepts

Abstract

This research aims to synthesize lipophilic berberine derivatives and evaluate their antiglioma effects on C6 and U87 cells.

References

23

Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma

Teri Kreisl, Lyndon Kim, Paul Duic et al. · Journal of Clinical Oncology · 2008 · 1.6K citations · Full text

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

Xiao-Ming Yin, Zoltán N. Oltvai, Stanley J. Korsmeyer · Nature · 1994 · 1.3K citations

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Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma

James J. Vredenburgh, Annick Desjardins, James E. Herndon et al. · Clinical Cancer Research · 2007 · 1.1K citations · Full text

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Temozolomide and treatment of malignant glioma.

Henry S. Friedman, Tracy Kerby, Hilary Calvert · PubMed · 2000 · 725 citations

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Gene Expression Profile of Glioblastoma Multiforme Invasive Phenotype Points to New Therapeutic Targets

Dominique B. Hoelzinger, Luigi Mariani, Joachim Weis et al. · Neoplasia · 2005 · 323 citations · Full text

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