Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

Brigitte Rigat, Christine Hübert, Pierre Corvol et al. · Nucleic Acids Research · 1992 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

Laurence Tiret, Brigitte Rigat, C Breda et al. · PubMed · 1992 · 1.2K citations

Medicine, Genetics, Molecular Genetics +6

A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease

Klaus Lindpaintner, Marc A. Pfeffer, Reinhold Kreutz et al. · New England Journal of Medicine · 1995 · 910 citations · Full text

Life Sciences, Cardiology, Genetics +11

Association of a human G-protein β3 subunit variant with hypertension

Winfried Siffert, Dieter Rosskopf, G Siffert et al. · Nature Genetics · 1998 · 732 citations

Medicine, Genetics, Molecular Genetics +12