Chromatin Fragments Resembling ν Bodies

Abstract

Fragments of chromatin resembling the spheroid chromatin units (v bodies) have been isolated from formaldehyde-fixed and sonicated chicken erythrocyte nuclei. Ultracentrifugal analyses demonstrated that monomer v bodies have a molecular weight of about 300,000 per particle, exhibit a protein to DNA ratio (by weight) of 1.22:1, and contain a DNA fragment with a molecular weight of approximately 140,000 per v body.