Changes in the Auditory Evoked Potentials and the Bispectral Index following Propofol or Propofol and Alfentanil

Abstract

MLAEP changes, like the BIS, correlate well with increasing sedation produced by propofol, and these changes in the MLAEP are independent of the presence of an opioid. Among all the MLAEP parameters, Pa and Nb latencies are the best predictors of increasing sedation and loss of consciousness.