Electrostatic Sequestration of PIP2 on Phospholipid Membranes by Basic/Aromatic Regions of Proteins

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

Bernard R. Brooks, Robert E. Bruccoleri, Barry D. Olafson et al. · Journal of Computational Chemistry · 1983 · 14.9K citations

Engineering, Molecular Biology, Empirical Energy Function +21

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Signal Transduction, Biochemistry, Natural Sciences +9

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

Anthony Nicholls, Kim A. Sharp, Barry Honig · Proteins Structure Function and Bioinformatics · 1991 · 5.2K citations

Energy of an Ion crossing a Low Dielectric Membrane: Solutions to Four Relevant Electrostatic Problems

Adrian Parsegian · Nature · 1969 · 848 citations

Membrane Structure, Electrical Engineering, Engineering +12

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

John E. Harlan, Philip J. Hajduk, Ho Sup Yoon et al. · Nature · 1994 · 758 citations

Proteinlipid Interaction, Signal Transduction, Molecular Physiology +8