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Exploring S1 plasticity and probing S1′ subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors

Germain Revelant, Mira Al-Lakkis-Wehbe, Marjorie Schmitt, Sarah Alavi, Céline Schmitt, Lionel Roux, Mounir Al-Masri, Nadège Schifano-Faux, Carmen Maiereanu, Céline Tarnus,

Bioorganic & Medicinal Chemistry · 2015 · 14 citations · 15 references

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15

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

Shripad V. Bhagwat, Johanna Lahdenranta, Ricardo J. Giordano et al. · Blood · 2001 · 346 citations · Full text

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The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing

Alan H. M. Wong, Dongxia Zhou, James M. Rini · Journal of Biological Chemistry · 2012 · 145 citations · Full text

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Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis

Kazuteru Fukasawa, Hideji Fujii, Yurika Saitoh et al. · Cancer Letters · 2006 · 140 citations

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CD13/APN regulates endothelial invasion and filopodia formation

Nenad Petrović, Wolfgang Schacke, J. Reed Gahagan et al. · Blood · 2007 · 131 citations · Full text

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The Design of Inhibitors for Medicinally Relevant Metalloproteins

F.E. Jacobsen, Jana A. Lewis, Seth M. Cohen · ChemMedChem · 2006 · 127 citations

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