DNA restriction fragments associated with α1-antitrypsin indicate a single origin for deficiency allele PI Z

Statistical Methods for Research Workers

American Journal of Clinical Pathology · 1945 · 11K citations

Methodological Development, Statistical Tests, Engineering +10

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

David Botstein, R. White, Mark H. Skolnick et al. · PubMed · 1980 · 8.4K citations

The Electrophoretic α; ₁ -Globulin Pattern of Serum in α; ₁ -Antitrypsin Deficiency

C.‐B. Laurell, Sten Eriksson · Scandinavian Journal of Clinical and Laboratory Investigation · 1963 · 1.4K citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

Stuart H. Orkin, Haig H. Kazazian, Stylianos E. Antonarakis et al. · Nature · 1982 · 933 citations

Genetic Analysis, Genetic Disorder, Genetics +11

Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

Harvey L. Sharp, Richard Bridges, William Krivit et al. · PubMed · 1969 · 704 citations

Hepatology, Autoimmune Disease, Allergy +8