Pituitary adenylate cyclase activating peptide, a novel VIP-like gut-brain peptide, relaxes the guinea-pig taenia caeci via apamin-sensitive potassium channels

Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells

Atsuro Miyata, Akira Arimura, Raymond R. Dahl et al. · Biochemical and Biophysical Research Communications · 1989 · 1.8K citations

Life Sciences, Biochemistry, Endocrinology +17

Apamin blocks certain neurotransmitter-induced increases in potassium permeability

Barbara E. C. Banks, C. M. Brown, Gillian M. Burgess et al. · Nature · 1979 · 354 citations

Life Sciences, Neuroscience, Pharmacology +11

Two High Affinity Binding Sites for Pituitary Adenylate Cyclase-Activating Polypeptide Have Different Tissue Distributions*

Brenda D. Shivers, Tamäs J. Görcs, Paul E. Gottschall et al. · Endocrinology · 1991 · 321 citations

Life Sciences, Biochemistry, Endocrinology +17

Pituitary adenylate cyclase activating peptide: A novel vasoactive intestinal peptide-like neuropeptide in the gut

F. Sundler, Eva Ekblad, Afaf Absood et al. · Neuroscience · 1992 · 241 citations

Life Sciences, Endocrinology, Physiology +14

Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract

Marcello Costa, John B. Furness, C. M. S. Humphreys · Naunyn-Schmiedeberg s Archives of Pharmacology · 1986 · 174 citations · Full text

Life Sciences, Pharmacology, Physiology +11