Rapid Communications in Mass Spectrometry · 1997 · 49 citations · 0 references
EngineeringOrganic ChemistryIon Mobility SpectrometryRapid MethodChemistryStability ConstantsSpectrochemical AnalysisInorganic CompoundAnalytical InstrumentationExcess Metal IonAnalytical ChemistryExcess Crown EtherInstrumentationBiophysicsChromatographyInorganic ChemistryBiochemistryIon MobilityCoordination ComplexMass SpectrometryProtein Mass SpectrometryMolecular ComplexMedicineIon StructureDrug Analysis
An easy and fast method using electrospray ionization mass spectrometry for determination of the stability constants (logKs) of different metal-ion complexes with crown and lariat crown ethers has been developed. This method has been verified with known logKs by using either excess crown ether or excess metal ion. Stability constants of Li+, Na+ and K+ with seven lariat crown ethers, including four new compounds, have been determined. © 1997 John Wiley & Sons, Ltd.