The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque

Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease

Satoshi Minoshima, Bruno Giordani, Stanley Berent et al. · Annals of Neurology · 1997 · 1.8K citations · Full text

Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies

C. A. Kitt, WF Simonds, DL Price et al. · Journal of Neuroscience · 1991 · 920 citations · Full text

Cellular Localization, Neurotransmitter, Neurochemical Biomarkers +19

Effects of Xanomeline, a Selective Muscarinic Receptor Agonist, on Cognitive Function and Behavioral Symptoms in Alzheimer Disease

N. Bodick, Walter Offen, Allan I. Levey et al. · Archives of Neurology · 1997 · 678 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

Ernest G. Peralta, Avi Ashkenazi, John Winslow et al. · Nature · 1988 · 666 citations

Adenylyl Cyclase, Molecular Pharmacology, Molecular Physiology +12

Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice

Stephan Anagnostaras, Geoffrey G. Murphy, Susan E. Hamilton et al. · Nature Neuroscience · 2002 · 543 citations

Neuropsychology, Medicine, Neuropharmacology +6