The Incremental Contribution of Clinical Breast Examination to Invasive Cancer Detection in a Mammography Screening Program

Abstract

CBE had modest incremental benefit to invasive cancer detection over mammography alone in a screening program, but also led to greater risk of false-positive results. These risks and benefits were greater in women with dense breasts. The balance of risks and benefits must be weighed carefully when evaluating the inclusion of CBE in a screening examination.