Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation

A method for measurement of analgesic activity on inflamed tissue.

Lowell O. Randall, Joseph J. Selitto · PubMed · 1957 · 1.6K citations

Inflammation, Health Sciences, Acute Pain +9

Prostaglandins, Aspirin-like Drugs and Analgesia

S. H. Ferreira · Nature New Biology · 1972 · 870 citations

Aspirin-like Drugs, Health Sciences, Pain Medicine +10

Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle

Christopher Miller, Edward Moczydlowski, Ramón Latorre et al. · Nature · 1985 · 797 citations · Full text

Cardiac Muscle, Protein Inhibitor, Signal Transduction +12

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.

A B Malmberg, T L Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1992 · 653 citations

Glucose, Sulfonylureas, and Neurotransmitter Release: Role of ATP-Sensitive K ⁺ Channels

Salvatore Amoroso, Heidy Schmid‐Antomarchi, Michel Fosset et al. · Science · 1990 · 408 citations