Relapse of acute promyelocytic leukemia with PML-RARα mutant subclones independent of proximate all-trans retinoic acid selection pressure

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Dynamics of chronic myeloid leukaemia

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Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor

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Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

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Medicine, Molecular Biology, Molecular Genetics +9

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment

Catherine Roche‐Lestienne, Valérie Soenen, Nathalie Grardel et al. · Blood · 2002 · 517 citations · Full text

Medicine, Hematology, Oncology +9