These results strongly indicate that IL-13, as well as IL-4, may be important in eotaxin-mediated eosinophilic inflammation in nasal mucosa. In addition, in nasal mucosa, fibroblasts are the major cell source for eotaxin.
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Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. Paul Ponath, Suofu Qin, D J Ringler, Journal of Clinical Investigation Mouse EotaxinLaboratory ImmunologyImmunologyHuman Eosinophil ChemoattractantSelective Recruitment | 1996 | 708 |
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