2013 · 123 citations · 1 references
Veterinary MedicineBioengineeringBiomedical EngineeringDiagnostic ImagingUltrasonographyUltrasoundAbdominal UltrasonographyBiomarkers Of Liver InjuryDiagnostic UltrasonographyElastographyUltrasound ImagingUltrasound PhysicsConsistency Of Measurement ResultsHepatic Fibrosis BiomarkersInterlaboratory StudyLiver ElastographyLiver Fibrosis BiomarkersLiver Fibrosis StagingLiver UltrasoundNoninvasive Fibrosis Biomarkers
An interlaboratory study of shear wave speed (SWS) estimation was performed. Commercial shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic Imagine, as well as several custom laboratory systems, were involved. Fifteen sites were included in the study. CIRS manufactured and donated 11 pairs of custom phantoms designed for the purposes of this investigation. Dynamic mechanical tests of equivalent phantom materials were also performed. The results of this study demonstrate that there is very good agreement among SWS estimation systems, but there are several sources of bias and variance that can be addressed to improve consistency of measurement results.
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