Concepedia

Anti‐interleukin‐31‐antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis

Øystein Grimstad, Yasushi Sawanobori, Christian Vestergaard, Janine Bilsborough, Uffe Bang Olsen, Christian Grønhøj‐Larsen, Kouji Matsushima

Experimental Dermatology · 2008 · 201 citations · 40 references

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Abstract

IL-31 antibody reduces scratching behaviour in an atopic dermatitis-like murine model during the onset of clinical skin manifestations. Our findings suggest IL-31 antibody as a new potential therapeutic approach for pruritus in atopic dermatitis and other pruritic diseases.

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