Solvent-Free Synthesis of Dihydropyridines and Acridinediones via a Salicylic Acid–Catalyzed Hantzsch Multicomponent Reaction

Abstract

Abstract A multicomponent Hantzsch synthesis of 1,4-dihydropyridines and acridinediones from commercially available aldehydes, ammonium acetate, and ethyl acetoacetate or dimedone, in the presence of salicylic acid as an efficient catalyst, in good yield and short reaction time is reported. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource(s): Full experimental and spectral details.]