Upregulation of P‐cadherin expression in the lesional skin of pemphigus, Hailey‐Hailey disease and Darier’s disease

Abstract

The present results clearly demonstrated that upregulation of P-cadherin expression occurs in the acantholysis in all the four blistering diseases PV, PF, HHD and DD. Upregulation of P-cadherin may be involved in the pathomechanism of both the autoimmune blistering diseases and the inherited blistering diseases.