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Critical development by design of a rugged HPLC-MS/MS method for direct determination of ibuprofen enantiomers in human plasma

Ibuprofen EnantiomersDrug DiscoveryMass SpectrometryPharmacologyHuman PlasmaAnalytical ChemistryRugged Hplc-ms/ms MethodClinical ChemistryLiquid ChromatographyChromatographic AnalysisMedicinePharmacokineticsChromatographyPharmaceutical ResearchDrug Analysis