Experimental Varicocele Induces p53-Dependent Germ Cell Apoptosis through Activation of γ-H2AX

Abstract

These results show that experimental varicocele may induce p53-dependent apoptosis through activation of γ-H2AX in the primary spermatocytes, and suggest that γ-H2AX may be related to apoptotic signal transduction in experimental varicocele.