Respiratory-gated positron emission tomography and breath-hold computed tomography coupling to reduce the influence of respiratory motion: Methodology and feasibility

Abstract

Respiratory-gated PET acquisition reduces the blurring effect and increases image contrast. However, Freq-based and Amp-based volumes are still influenced by inappropriate attenuation correction and misregistration of mobile lesions on CT images. The proposed BH-based method both reduces motion artifacts and improves PET-CT registration.