Biophysical stimulation induces demyelination via an integrin‐dependent mechanism

Michael Lin, Laura S. Frieboes, Maryam Forootan, Winnie A. Palispis, Tahseen Mozaffar, Matiar Jafari, Oswald Steward, Christine M. Gall, Ranjan Gupta

Annals of Neurology · 2012 · 14 citations · 35 references

DOIFull text

Open access

Abstract

These results indicate that myelin is sensitive to CNC injury and support the novel concept that myelinating cocultures respond directly to mechanical loading via activating an integrin signaling cascade.

References

35