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Experimental application of the median-effect principle for in vitro quantification of the combined inhibitory activities of clavulanic acid and imipenem against IRT-4 β-lactamase

Inhibitory ActivityMedicinal ChemistryExperimental ApplicationAntimicrobial SusceptibilityAntibioticsMedian-effect PrincipleVitro QuantificationMedicinePharmacotherapyAntibacterial AgentMicrobiologyAntimicrobial PharmacokineticsAntimicrobial PharmacodynamicsAntimicrobial CompoundPharmacologyAntimicrobial ChemotherapyAntimicrobial ResistanceDrug Analysis