Inhibition of Telomerase Activity as a Measure of Tumor Cell Killing by Cisplatin in Squamous Cell Carcinoma Cell Line

Abstract

The results of the present studies on in vitro squamous cell carcinoma cell lines indicate that telomerase activity inhibition can be used as a marker of tumor cell killing by CDDP. Therefore, the present investigation provides a rational basis for an in vitro chemosensitivity assay based on telomerase activity evaluation.