The Distribution, Release Kinetics, and Biocompatibility of Triamcinolone Injected and Dispersed in Silicone Oil

Abstract

Intravitreally injected TA does not mix with silicone oil. TA crystals that sediment at the lower border of a silicone oil bubble may be harmful to retinal cells. A suspension of TA in silicone oil may exhibit safer extended release over several days.