Reactions with the Arylhydrazones of α-Cyanoketones: Utility of Arylhydrazonomesoxalonitriles for the Synthesis of Azoles and Azolines

Abstract

The arylhydrazonomesoxalonitriles derivatives 1 a - c were utilised for the synthesis of several new pyrimidine, pyridines, triazine and isoxazole derivatives. Compound 1 a reacted with alkyl halides to yield the N-alkyl derivatives 12a, b. The latter reacted with hydrazines to yield the amidrazones 13 a, b.