Internal Medicine · 2010 · 32 citations · 8 references
MedicineCardiologyInternal MedicineEating DisordersPathophysiologyStructural Heart DiseaseAnorexia NervosaCardiac ArrhythmiasCardiovascular DiseaseHeart FailureVentricular TachycardiaLife-threatening ArrhythmiasQt Interval AnalysisQt Interval AssessmentRisk IndicatorsSudden Cardiac Death Predisposition
We report the case of a 57-year-old woman with anorexia nervosa showing evidence of "tako-tsubo" cardiomyopathy complicated by several syncopes due to recurrent episodes of torsades de pointes. Prolongation of QT interval and QT dispersion have been reported both in the "tako-tsubo" cardiomyopathy and in anorexia nervosa. The QT prolongation and the QT dispersion has been linked as risk indicators for sudden cardiac death. The combination of "tako-tsubo" cardiomyopathy with a condition associated with the prolongation of QT and/or with an increase of QT dispersion, such as anorexia nervosa, makes the acute and subacute prognosis of this disease much more severe than usual.
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Electrocardiographic abnormalities in patients with anorexia nervosa.
J G B Thurston, Peta Marks · Heart · 1974 · 92 citations · Full text