Prediction of Outcome in Borderline Personality Disorder

Abstract

In order to study outcome heterogeneity in borderline personality disorder (BPD), the author performed correlations of more than 50 predictor variables with 7 independent outcome dimensions, assessed at a mean of 14 years after the index hospitalization, in a group of 33 BPD patients selected for minimal comorbidity with affective illness, substance dependence, or other personality disorders. Predictors are reported that achieved statistical significance, generally across multiple outcome dimensions. Results suggest that outcome prediction in BPD differs from outcome prediction in schizophrenia. A history of parental divorce, long duration of prior hospitalization, and the presence of specific personality disorder criteria predicted poor outcome in BPD. The presence of self-destructive acts during the index treatment predicted good outcome.