Protective effects of amide constituents from the fruit of Piper chaba on d-galactosamine/TNF-α-induced cell death in mouse hepatocytes

Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice

Gisa Tiegs, Marc Wolter, Albrecht Wendel · Biochemical Pharmacology · 1989 · 307 citations

Veterinary Medicine, Immunology, Pathobiology +16

Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice

Marina A. Freudenberg, Chris Galanos · Infection and Immunity · 1991 · 224 citations · Full text

Life Sciences, Immunology, Microbiology +16

Tumor Necrosis Factor-induced Toxic Liver Injury Results from JNK2-dependent Activation of Caspase-8 and the Mitochondrial Death Pathway

Yongjun Wang, Rajat Singh, Jay H. Lefkowitch et al. · Journal of Biological Chemistry · 2006 · 205 citations · Full text

Veterinary Medicine, Pathobiology, Toxicology +17

Inhibitory effect and action mechanism of sesquiterpenes from zedoariae rhizoma on d-galactosamine / lipopolysaccharide-induced liver injury

Hisashi Matsuda, Kiyofumi Ninomiya, Toshio Morikawa et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 179 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Structures of New Dammarane-Type Triterpene Saponins from the Flower Buds of <i>Panax </i><i>n</i><i>otoginseng</i> and Hepatoprotective Effects of Principal Ginseng Saponins

Masayuki Yoshikawa, Toshio Morikawa, Yousuke Kashima et al. · Journal of Natural Products · 2003 · 171 citations

Pharmacy, Botany, Medicinal Chemistry +9