ISRN Obstetrics and Gynecology · 2012 · 20 citations · 35 references
MedicineOncologySurgeryAssisted Reproductive TechnologiesFertilityInfertilityFemale InfertilityFertility PreservationOocyte CryopreservationCryopreservationDonor OocytesFemale Fertility PreservationIn Vitro MaturationOvarian TranspositionRadical Trachelectomy
With improved survival rates among cancer patients, fertility preservation is now being recognized as an issue of great importance. There are currently several methods of fertility preservation available in female cancer patients and the options and techniques via assisted reproduction and cryopreservation are increasing, but some are still experimental and continues to be evaluated. The established means of preserving fertility include embryo cryopreservation, gonadal shielding during radiation therapy, ovarian transposition, conservative gynecologic surgery such as radical trachelectomy, donor embryos/oocytes, gestational surrogacy, and adoption. The experimental methods include oocyte cryopreservation, ovarian cryopreservation and transplantation, in vitro maturation, and ovarian suppression. With advances in methods for the preservation of fertility, providing information about risk of infertility and possible options of fertility preservation to all young patients with cancer, and discussing future fertility with them should be also considered as one of the important parts of consultation at the time of cancer diagnosis.
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Ahmedin Jemal, Thomas S. Murray, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2005 · 5.5K citations · Full text
Livebirth after orthotopic transplantation of cryopreserved ovarian tissue
Jacques Donnez, MM Dolmans, Dominique Demylle et al. · The Lancet · 2004 · 1.6K citations
Medicine, Gynecology, Surgery +13
The radiosensitivity of the human oocyte
William H. Wallace, Angela Thomson, Tom Kelsey · Human Reproduction · 2003 · 681 citations
Leslie R. Schover, Lisa Rybicki, Beth Anne Martin et al. · Cancer · 1999 · 559 citations · Full text
Medicine, Child Health, Oncology +14