Infection Control and Hospital Epidemiology · 1999 · 49 citations · 10 references
MedicineInfectious Disease ControlInfectious DiseasesHepatologyInfection PreventionInjury SurveillanceContact TracingHealthcare-associated Infection PreventionInfectious Disease Molecular TestingInfectious Disease ScreeningInfectious Disease SurveillanceViral HepatitisHepatitis C InfectionHepatitis C ManagementHepatitis C Virus ManagementHepatitis C Virus TransmissionHepatitis Virus TestingNeedlestick InjuriesNeedlestick Injury ManagementViral Hepatitis Assessment
The rate of transmission and management of needlestick injuries from hepatitis C virus (HCV) patients to healthcare workers is still a matter of debate. We used a stringent protocol using monthly transaminase levels and polymerase chain reaction for HCV RNA to monitor 53 healthcare workers prospectively for up to 6 months following needle injuries from HCV-positive patients. Evidence of transmission of HCV was found in only 2 workers (4%) with mild asymptomatic infection, one of which resolved spontaneously. Based on our experience, we now use a less-intensive follow-up protocol. Further investigation is required to determine the most cost-effective method to monitor individuals who suffer a needlestick injury from an HCV-positive patient.
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Hepatitis C Virus Infection in Medical Personnel After Needlestick Accident
Takehiro Mitsui, Keiko Iwano, Kazuo Masuko et al. · Hepatology · 1992 · 426 citations
Hepatitis B e Antigen and Infectivity of Hepatitis B Virus
Toshio Shikata, T. Karasawa, Kenji Abe et al. · The Journal of Infectious Diseases · 1977 · 290 citations