A germline mutation abolishing the original stop codon of the human adenine phosphoribosyltransferase (APRT) gene leads to complete loss of the enzyme protein

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

Nucleic Acid Chemistry, Engineering, Natural Sciences +7

Role of a Peptide Tagging System in Degradation of Proteins Synthesized from Damaged Messenger RNA

Kenneth C. Keiler, P R Waller, Robert T. Sauer · Science · 1996 · 1.1K citations

Peptide Engineering, Molecular Biology, Escherichia Coli +19

PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates.

Wayne M. Barnes · Proceedings of the National Academy of Sciences · 1994 · 1K citations · Full text

Genetics, Bacteriophage, Dna Analysis +20

Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3.

Galina A. Zhouravleva, Ludmila Frolova, Xavier Le Goff et al. · The EMBO Journal · 1995 · 597 citations · Full text

Systems Biology, Signal Transduction, Protein Function +7

A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor

L Iu Frolova, Xavier Le Goff, Hanne H. Rasmussen et al. · Nature · 1994 · 411 citations

Protein Function, Protein Expression, Eukaryotic Protein Family +6