4,4′‐Coupled bis(isoquinolines)

Abstract

Abstract Reaction of the eneamine 1 formed in situ from isoquinoline and sodium triethylborohydride with aromatic dialdehydes 3 produces 4,4′‐coupled bis(isoquinolines) 4 in good yields. These compounds are readily oxidized with manganese dioxide to the corresponding diketones 5 .