Polyadenylic Acid Sequences in the Virion RNA of Poliovirus and Eastern Equine Encephalitis Virus

John A. Armstrong, Mary Edmonds, Hiroshi Nakazato, Bruce A. Phillips, Maurice H. Vaughan

Science · 1972 · 149 citations · 22 references

Concepts

Abstract

Poliovirus virion RNA contains a single covalently bound sequence of polyadenylic acid which is approximately 49 nucleotides long. A single, slightly longer polyadenylic acid sequence is contained in Eastern Equine Encephalitis virus RNA. Since these viruses are otherwise dissimilar these sequences may play a common role in viral replication, possibly in translation of the viral RNA.

References

22