Clinical Features and Course of Patients with Glaucoma with the E50K Mutation in the Optineurin Gene

Abstract

In this study, subjects with glaucoma who had the OPTN E50K mutation were found to have NTG that appeared to be more severe than that in a control group of subjects with NTG without this mutation. The findings emphasize the importance of early detection and treatment of glaucoma in such individuals, to minimize visual loss.