The Inhibitory Effect of Intravenous Lidocaine Infusion on Tinnitus after Translabyrinthine Removal of Vestibular Schwannoma: A Double-Blind, Placebo-Controlled, Crossover Study

Abstract

Intravenous infusion of lidocaine has a statistically significant inhibitory effect on tinnitus in patients who have previously undergone translabyrinthine removal of a vestibular schwannoma. The site of action of lidocaine in this instance must be in the central auditory pathway, as the cochlear and vestibular nerves are sectioned during surgery, and this finding has important implications for the task of identifying other agents that will have a similar tinnitus-inhibiting effect.