Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

A Fabiato, F Fabiato · PubMed · 1979 · 1.6K citations

Tissue Engineering, Mechanobiology, Engineering +14

The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

Journal of Biological Chemistry · 1975 · 920 citations · Full text

Molecular Biology, Mm Mgcl2, Cellular Physiology +16

Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study.

Piero Pollesello, Martti Ovaska, Juha Kaivola et al. · Journal of Biological Chemistry · 1994 · 233 citations · Full text

Levosimendan Binds, Molecular Pharmacology, Cardiac Muscle +14

Site-directed Mutation of the Trigger Calcium-binding Sites in Cardiac Troponin C

John A. Putkey, H. Lee Sweeney, Sean Campbell · Journal of Biological Chemistry · 1989 · 175 citations · Full text

Cardiac Muscle, Molecular Biology, Cytoskeleton +18

Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments.

R. John Solaro, Giovanni Gambassi, David M. Warshaw et al. · Circulation Research · 1993 · 163 citations · Full text

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +12