Crown Gall Disease and Prospects for Genetic Manipulation of Plants

Abstract

Agrobacterium tumefaciens incites crown gall tumors when bacterial DNA integrates into plant nuclear DNA. Plant cells can express these integrated bacterial genes. Following insertion of desired genes into bacterial DNA using recombinant DNA techniques, this system permits introduction of these new genes into plant DNA. We discuss the potential for genetic manipulation of plants using Agrobacterium tumefaciens and the related organism Agrobacterium rhizogenes.

References

Page 1

	Year	Citations
Chemical regulation of growth and organ formation in plant tissues cultured in vitro. Folke Skoog, Carlos O. Miller PubMed BiologyOrgan FormationHealth SciencesBotanyNatural Sciences	1957	2.2K
Stable incorporation of plasmid DNA into higher plant cells: the molecular basis of crown gall tumorigenesis Mary-Dell Chilton, Martin Drummond, Donald J. Merlo, Cell Plant Molecular BiologyPlant BiologyNatural SciencesGeneticsMolecular Biology	1977	1.1K
Large plasmid in Agrobacterium tumefaciens essential for crown gall-inducing ability Nicolas Van Larebeke, Gilbert Engler, M. Holsters, Nature BacteriologyBiotechnologyMicrobiologyMolecular MicrobiologyLarge Plasmid	1974	737
Agrobacterium rhizogenes inserts T-DNA into the genomes of the host plant root cells Mary-Dell Chilton, David Tepfer, Annik Petit, Nature BiologyAgrobacterium RhizogenesPlant Molecular BiologyPlant-microbe InteractionGenetics	1982	721
Plasmid required for virulence of Agrobacterium tumefaciens Brian Watson, Thomas C. Currier, M P Gordon, Journal of Bacteriology BiologyStrain C-58Virulence PlasmidDonor Strain C-58Medicine	1975	676
The host range of crown gall Marcel De Cleene, Jozef De Ley The Botanical Review Crown GallAstroinformatics	1976	675
Genetic analysis of crown gall: Fine structure map of the T-DNA by site-directed mutagenesis David Garfinkel Cell BiologyGenetic AnalysisCrown GallFine Structure MapDna Sequencing	1981	577
A restriction enzyme cleavage map of Tn5 and location of a region encoding neomycin resistance Richard A. Jorgensen, Steven J. Rothstein, Williams S. Reznikoff Molecular and General Genetics MGG Antimicrobial Resistance GeneMolecular BiologyNeomycin ResistanceMicrobiologyMolecular Microbiology	1979	576
Supercoiled circular DNA in crown-gall inducing Agrobacterium strains I. Zaenen, Nicolas Van Larebeke, H. Teuchy, Journal of Molecular Biology Circular DnaBacteriologyMolecular BiologyMicrobiologyMolecular Microbiology	1974	476
The functional organization of the nopaline A. tumefaciens plasmid pTiC58 Marcelle Holsters, B. Silva, F. Van Vliet, Plasmid Protein AssemblyBiochemistryNatural SciencesProtein X-ray CrystallographyMolecular Biology	1980	460

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