IRES-Dependent Second Gene Expression Is Significantly Lower Than Cap-Dependent First Gene Expression in a Bicistronic Vector

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Hitoshi Niwa, Ken‐ichi Yamamura, Jun‐ichi Miyazaki · Gene · 1991 · 5.2K citations

Systems Biology, Engineering, Efficient Selection +11

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.8K citations

Point Mutations, Natural Sciences, Genetics +9

Improved retroviral vectors for gene transfer and expression.

A. Dusty Miller, G J Rosman · PubMed · 1989 · 2K citations · Full text

High-titer Virus Stocks, Viral Replication, Murine Retrovirus-based Vectors +14

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

Jerry Pelletier, Nahum Sonenberg · Nature · 1988 · 1.9K citations

Internal Initiation, Poliovirus Rna, Eukaryotic Mrna +13

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

F Liu, Young Song, D Liu · Gene Therapy · 1999 · 1.7K citations

Xenotransplantation, Engineering, Molecular Biology +10