Cholinergic-dopaminergic interactions and the mechanisms of action of antidepressants

A CHOLINERGIC-ADRENERGIC HYPOTHESIS OF MANIA AND DEPRESSION

DavidS. Janowsky, JohnM. Davis, M. Khaled El‐Yousef et al. · The Lancet · 1972 · 1.1K citations

Medicine, Neuroscience, Pharmacology +10

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

Stephen J. Peroutka, Solomon H. Snyder · Science · 1980 · 838 citations

Medicine, Pharmacology, Psychiatry +17

Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats

Peter H. Kelly, Susan D. Iversen · European Journal of Pharmacology · 1976 · 714 citations

Life Sciences, Neurobiology, Neuroscience +16

A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-Trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine

David T. Wong, Jong S. Horng, Frank P. Bymaster et al. · Life Sciences · 1974 · 477 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Antidepressants and the Muscarinic Acetylcholine Receptor

Solomon H. Snyder · Archives of General Psychiatry · 1977 · 429 citations

Medicine, Pharmacology, Pharmacotherapy +17