Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton, David Clayton, Lon R. Cardon et al. · Nature · 2007 · 9.6K citations · Full text

Genome-wide Association Study, Disease Susceptibility, Disease Etiology +9

A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

Ruth McPherson, Alexander Pertsemlidis, Nihan Kavaslar et al. · Science · 2007 · 1.6K citations · Full text

Genetics, Genetic Epidemiology, Human Polymorphism +20

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

Kyoko L. Yap, SiDe Li, Ana M. Muñoz-Cabello et al. · Molecular Cell · 2010 · 1.4K citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +11

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

Yasuhito Kotake, Toshiyuki Nakagawa, Kyoko Kitagawa et al. · Oncogene · 2010 · 974 citations · Full text

Non-coding Rna Anril, Prc2 Recruitment, Rna Biology +9

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

Anna Helgadóttir, Kristinn P. Magnússon, Sólveig Grétarsdóttir et al. · Nature Genetics · 2008 · 723 citations

Cardiomyopathy, Vascular Disease, Cardiovascular Disease +12