Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Panos Deloukas, Audrey Duncanson, Dominic Kwiatkowski et al. · Nature · 2007 · 9.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

Ruth McPherson, Alexander Pertsemlidis, Nihan Kavaslar et al. · Science · 2007 · 1.6K citations · Full text

Medicine, Genetics, Molecular Genetics +17

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

Kyoko L. Yap, SiDe Li, Ana M. Muñoz-Cabello et al. · Molecular Cell · 2010 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

Yasuhito Kotake, Toshiyuki Nakagawa, Kyoko Kitagawa et al. · Oncogene · 2010 · 982 citations

Medicine, Molecular Biology, Molecular Genetics +13

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

Anna Helgadóttir, Kristinn P. Magnússon, Sólveig Grétarsdóttir et al. · Nature Genetics · 2008 · 728 citations

Medicine, Genetics, Molecular Genetics +9