Gene and protein structure of a β-crystallin polypeptide in murine lens: relationship of exons and structural motifs

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

Michael Grunstein, David S. Hogness · Proceedings of the National Academy of Sciences · 1975 · 3.5K citations · Full text

Hybrid Plasmids, Cole1 Hybrid Plasmids, Different Hybrid Plasmids +21

Why genes in pieces?

Walter Gilbert · Nature · 1978 · 2.3K citations · Full text

Genetics, Genomic Mechanism, Genetic Engineering +5

Nucleotide sequence of the rightward operator of phage lambda.

Tom Maniatis, Andrea Jeffrey, Dennis G. Kleid · Proceedings of the National Academy of Sciences · 1975 · 2.1K citations · Full text

Biology, Dna Sequencing, Natural Sciences +15

A graphics model building and refinement system for macromolecules

T. Alwyn Jones · Journal of Applied Crystallography · 1978 · 1.8K citations

Engineering, Molecular Biology, Graphics Model Building +16